PGE synthase rabbit pAb - ES3188

PGE synthase rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3188-50, ES3188-100

Citations, Manuals and MSDS Available upon request.

Background: prostaglandin E synthase (PTGES) Homo sapiens The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008],

Alternate Name: PTGES; MGST1L1; MPGES1; PGES; PIG12; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PGE synthase. AA range:30-79

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 17kD

Human Gene ID: 9536

Human SWISS Prot NO: O14684

Subcellular Location: Membrane; Multi-pass membrane protein. Cytoplasm, perinuclear region. Colocalizes with PTGS1/COX-1 and PTGS2/COX-2 in the perinuclear compartment.

Research Use Only