PGR Monoclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-22105-60, E-AB-22105-120, E-AB-22105-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PR
Target Synonym: NR3C3; Nuclear receptor subfamily 3 group C member 3; PGR; PR; PRA; PRB; PRGR; Progesterone receptor; Progestin receptor form A; Progestin receptor form B
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Neuroscience, Signal Transduction
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Application: IHC-p, IF
Isotype: IgG
Clonality: Monoclonal
Clone No.: Clone:1A5
UNIProt ID: P06401
Background: The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation.Isoform A: inactive in stimulating c-Src/MAPK signaling on hormone stimulation.Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone.
Concentration: 1 mg/mL
Immunogen: Synthetic Peptide
Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Purification Method: Protein A purification
Dilution: IHC 1:100-1:300, IF 1:100-200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only