Product Description

PHD2 / prolyl hydroxylase Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40613-50, BS40613-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellμlar oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IP

Alternate Names: EGLN1, C1orf12, ECYT3, HIFPH2, HPH2, PHD2, SM-20, SM20, ZMYND6,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human PHD2 / prolyl hydroxylase

Dilution: WB 1:500~1:2000 IP 1:50

Purification: Affinity-chromatography

Specificity: PHD2 / prolyl hydroxylase Antibody detects endogenous levels of total PHD2 / prolyl hydroxylase

Molecular Weight: 46kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9GZT9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only