Product Description

PHF17 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS8143-50, BS8143-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Jade-1, also known as PHF17 (PHD finger protein 17), is an 842 amino acid protein that localizes to both the cytoplasm and the nucleus and contains two PHD-type zinc fingers. Expressed at high levels in kidney tissue and also present in heart, pancreas and liver, Jade-1 functions as a transcriptional coactivator that, via its PHD zinc fingers, promotes the TIP30-dependent acetylation of Histone H4. Additionally, Jade-1 is thought to promote apoptosis and is down-regμlated in renal carcinoma cells, suggesting a possible role in tumor suppression. Three isoforms of Jade-1, two of which are designated JADE1L and JADE1S, are produced via alternative splicing events. The gene encoding Jade-1 maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IF

Alternate Names: Protein Jade-1, Jade family PHD finger protein 1, PHD finger protein 17, JADE1, KIAA1807, PHF17

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant fμll length Human PHF17.

Dilution: WB: 1:500~1:2000
IF: 1:50~1:200

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: PHF17 polyclonal antibody detects endogenous levels of PHF17 protein.

Molecular Weight: ~ 108 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q6IE81

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only