Product Description

PHKB Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28734-50, RA28734-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: phosphorylase kinase regulatory subunit beta (PHKB) Homo sapiens Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, encoded by this gene, which is a member of the phosphorylase b kinase regulatory subunit family. The gamma subunit also includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9B, also known as phosphorylase kinase deficiency

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: PHKB, Phosphorylase b kinase regulatory subunit beta, Phosphorylase kinase subunit beta

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 124

Protein Molecular Weight (kDa): 124

Storage: -20°C/1 year

Human Gene ID: 5257

Human SwissProt Number: Q93100

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only