Product Description

PHO1 Polyclonal Antibody

Catalogue Numbers: BS5613-50, BS5613-100

Sizes: 50µl, 100µl

Alternative Name: DNA dC->dU-editing enzyme APOBEC-3A; A3A; Phorbolin-1; APOBEC3A; Phorbolin 1; Phorbolin1; PHO-1

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P31941

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: APOBEC3A (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A), also known as PHO1 or ARP3 or PHRBN is a 199 amino acid protein that belongs to the cytidine deaminase family. Expressed in keratinocytes, as well as in peripherical leukocytes, APOBEC3A may be implicated in cell growth and cell cycle control. The gene encoding APOBEC3A is one of seven related genes which map to a cluster on chromosome 22 and are thought to play a role in tumor transformation and metastasis, as well as in host-associated antiviral activity. Chromosome 22 houses over 500 genes, some of which are involved in Phelan-McDermid syndrome, schizophrenia and Neurofibromatosis type 2.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PHO1 polyclonal antibody detects endogenous levels of PHO1 protein.

Bioworld Molecular Weight: ~ 23 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot (WB) analysis of PHO1 polyclonal antibody at 1:500 dilution
Lane 1: HEK293T cell lysate
Lane 2: sp2/0 cell lysate
Lane 3: H9C2 cell lysate

Immunogen: Synthetic peptide, corresponding to amino acids 67-112 of Human PHO1.

Conjugate: Unconjugated

Modification: Unmodified