Phospho-Amyloid Precursor Protein (Thr743) Monoclonal Antibody-MB11848

Phospho-Amyloid Precursor Protein (Thr743) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11848-50, MB11848-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P05067

Host: Rabbit

Reactivity: Human, Rat

Applications: WB, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Background: APP a cell surface receptor that influences neurite growth, neuronal adhesion and axonogenesis. Cleaved by secretases to form a number of peptides, some of which bind to the acetyltransferase complex Fe65/TIP60 to promote transcriptional activation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 87 kDa; Observed MW: 100 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Phospho-Amyloid Precursor Protein in LNcap using Phospho-Amyloid Precursor Protein antibody, and DAPI., Western blot analysis of Phospho-Amyloid Precursor Protein in Hela, U2OS, C6 lysates using Phospho-Amyloid Precursor Protein antibody.

Alternative Name: APP; A4; AD1; Amyloid beta A4 protein; ABPP; APPI; APP; Alzheimer disease amyloid protein; Cerebral vascular amyloid peptide; CVAP; PreA4; Protease nexin-II; PN-II

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr743 of human Amyloid Precursor Protein

Conjugate: Unconjugated

Modification: Phosphorylated