Product Description

Phospho-ATF4 (Ser219) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16313-50, BZ16313-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P18848

Host: Rabbit

Reactivity: Human

Applications: WB

All Applications: WB: 1/500-1/1000

Background: ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-ATF4 in COLOLysates using Phospho-ATF4 antibody.

Bioworld Molecular Weight: Calculated MW: 39 kDa; Observed MW: 39 kDa

Specificity: IgG

Alternative Name: Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67

Immunogen: Synthetic peptide of human ATF4

Conjugate: Unconjugated

Modification: Phosphorylated