Product Description

Phospho-BTK (Y551) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40246-50, BS40246-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Bruton's tyrosine kinase (Btk) is a member of the Btk/Tec family of cytoplasmic tyrosine kinases. Like other Btk family members, it contains a pleckstrin homology (PH) domain and Src homology SH3 and SH2 domains. Btk plays an important role in B cell development. Activation of B cells by various ligands is accompanied by Btk membrane translocation mediated by its PH domain binding to phosphatidylinositol-3, 4, 5-trisphosphate.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, ICC/IF

Alternate Names: BTK, AGMX1, AT, ATK, XLA, PSCTK1, B-cell progenitor kinase, BPK, Bruton tyrosine kinase, Tyrosine-protein kinase BTK, IMD1,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-BTK (Y551)

Dilution: WB 1:500~1:2000 ICC/IF 1:50~1:200

Purification: Affinity-chromatography

Specificity: Phospho-BTK (Y551) Antibody detects endogenous levels of Phospho-BTK (Y551)

Molecular Weight: 74kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q06187

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only