Phospho-Cadherin 5 (Tyr731) Polyclonal Antibody-BZ16322

Phospho-Cadherin 5 (Tyr731) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16322-50, BZ16322-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P33151

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: This gene is a classical cadherin from the cadherin superfamily and is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Functioning as a classic cadherin by imparting to cells the ability to adhere in a homophilic manner, the protein may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. An alternative splice variant has been described but its full length sequence has not been determined.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Cadherin 5 in HepG2Lysates using Phospho-Cadherin 5 antibody.

Bioworld Molecular Weight: Calculated MW: 88 kDa; Observed MW: 130 kDa

Specificity: IgG

Alternative Name: CDH5; Cadherin-5; 7B4 antigen; Vascular endothelial cadherin; VE-cadherin; CD antigen CD144

Immunogen: Synthetic peptide of human CDH5

Conjugate: Unconjugated

Modification: Phosphorylated