Phospho-CD31 (Tyr713) Polyclonal Antibody-BZ16481

Phospho-CD31 (Tyr713) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16481-50, BZ16481-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P16284

Host: Rabbit

Reactivity: Human, Mouse

Applications: ELISA, IHC-F, IHC-P, WB, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: PECAM-1 a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 83 kDa; Observed MW: 150 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: EnzymeLinked Immunosorbent Assay for Immunogen Phospho-peptide and NonPhospho-peptide, using PECAM1 (Phospho-Tyr71antibody, Immunofluorescence analysis of Phospho-CD31 in HeLa using Phospho-CD31 antibody. The picture on the right is blocked with the Phospho- peptide., Western blot analysis of Phospho-CD31 in HepG2 lysates using Phospho-CD31 antibody. The Lane on the right is blocked with the Phospho- peptide.

Alternative Name: Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; CD antigen CD31

Immunogen: The antiserum was produced against synthesized peptide derived from human PECAM-1 around the phosphorylation site of Tyr713. AA range:686-735

Conjugate: Unconjugated

Modification: Phosphorylated