Phospho-CD4 (S433) Polyclonal Antibody - BT-PHS01138

Phospho-CD4 (S433) Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-PHS01138-20, BT-PHS01138-50, BT-PHS01138-100

Citations, Manuals and MSDS Available upon request.

Background: CD4 (CD4 molecule) encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. CD4 is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in CD4.

Research Areas: Immunology; Stem Cells

Target Protein: CD4

Applications: IHC-p, IF, ELISA

Reactivity: Human, mouse

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Phospho-CD4 (S433) Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 51111

UniProt Accession: Human: P01730; Mouse: P06332

Synonyms: CD4; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3; CD antigen CD4

GeneID: Human: 920; Mouse: 12504

Research Use Only