Phospho-CDC6 (Ser106) Monoclonal Antibody-MB10711

Phospho-CDC6 (Ser106) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10711-50, MB10711-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q99741

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated.Cdc6 has recently been shown to play an important role in the intra-S-phase p21 Waf1/Cip1-dependent DNA damage response. Both cdc6 and CDT1 are degraded by the ubiquitin proteasome pathway in response to DNA damage associated with re-replication.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Cdc6 in JurkatLysates using Phospho-CDC6 antibody.

Bioworld Molecular Weight: Calculated MW: 63 kDa; Observed MW: 63 kDa

Specificity: IgG

Alternative Name: CDC6; CDC18L; Cell division control protein 6 homolog; CDC6-related protein; Cdc18-related protein; HsCdc18; p62(cdc6); HsCDC6

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser106 of human Cdc6

Conjugate: Unconjugated

Modification: Phosphorylated