Product Description

Phospho-Chk1 (S296) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40215-50, BS40215-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Chk1 kinase acts downstream of ATM/ATR kinase and plays an important role in DNA damage checkpoint control, embryonic development, and tumor suppression. Activation of Chk1 involves phosphorylation at Ser317 and Ser345 by ATM/ATR, followed by autophosphorylation of Ser296. Activation occurs in response to blocked DNA replication and certain forms of genotoxic stress.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Checkpoint, S. pombe, homolog of, 1, CHEK1, CHK1, CHK1 checkpoint homolog (S. pombe), Serine/threonine-protein kinase Chk1,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-Chk1 (S296)

Dilution: WB 1:500~1:2000

Purification: Affinity-chromatography

Specificity: Phospho-Chk1 (S296) Antibody detects endogenous levels of Phospho-Chk1 (S296)

Molecular Weight: 54kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O14757

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only