Product Description

Phospho-EGFR (Tyr1068) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB10854-50, MB10854-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregμlin, betacellμlin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor resμlts in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecμles and lysosomal degradation.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC-F, IHC-P, ICC/IF

Alternate Names: EGFR, ERBB, ERBB1, HER1, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1068 of human EGFR

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 134 kDa, Observed MW: 175 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00533

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only