Phospho-EGFR (Tyr1092) Monoclonal Antibody-MB10855

Phospho-EGFR (Tyr1092) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10855-50, MB10855-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P00533

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 134 kDa; Observed MW: 175 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of EGFR in C6, 3T3, Hela lysates using Phospho-EGFR antibody., Immunohistochemistry analysis of paraffin-embedded Human breast cancer using Phospho-EGFR antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval.

Alternative Name: EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1092 of human EGFR

Conjugate: Unconjugated

Modification: Phosphorylated