Product Description

Phospho-ERK1/2 (Tyr222/Tyr205) (1H4) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB3271-50, MB3271-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellμlar context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regμlation of transcription, translation, cytoskeletal rearrangements.

Category: Primary Antibody

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: IHC-P

Alternate Names: MAPK1/MAPK3

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: Synthetic peptide conjugated to KLH.

Dilution: IHC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG1

Molecular Weight: -

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P27361/P28482

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only