Product Description

Phospho-Estrogen Receptor alpha (Ser118) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16290-50, BZ16290-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regμlates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regμlate ER activity. ER is phosphorylated on mμltiple sites.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC-P, ICC/IF

Alternate Names: ESR1, Era, Eralpha, Estrogen receptor, Estradiol receptor, ER-alpha, Estrogen receptor 1, NR3A1, ER, ESR, ESRA, Estrogen receptor alpha

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: Synthetic peptide of human ESR1

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 66 kDa, Observed MW: 66 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P03372

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only