Phospho-Estrogen Receptor alpha (Ser118) Polyclonal Antibody-BZ16290

Phospho-Estrogen Receptor alpha (Ser118) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16290-50, BZ16290-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P03372

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Background: ER (estrogen receptor 1) a member of the steroid receptor superfamily, contains highly conserved DNA binding (DBD) and ligand binding domains (LBD). Through its estrogen-independent and estrogen-dependent activation domains (AF-1 and AF-2, respectively), ER regulates transcription by recruiting coactivator proteins and interacting with general transcriptional machinery. Phosphorylation provides an important mechanism to regulate ER activity. ER is phosphorylated on multiple sites.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 66 kDa; Observed MW: 66 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Estrogen Receptor alpha in MDAMB435 lysates using Phospho-Estrogen Receptor alpha antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using Estrogen Receptora antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-Estrogen Receptor alpha in MCF-7 cells using Estrogen Receptora antibody.

Alternative Name: ESR1; Era; Eralpha; Estrogen receptor; Estradiol receptor; ER-alpha; Estrogen receptor 1; NR3A1; ER; ESR; ESRA; Estrogen receptor alpha

Immunogen: Synthetic peptide of human ESR1

Conjugate: Unconjugated

Modification: Phosphorylated