Phospho-FRS2 (Tyr436) Polyclonal Antibody-BZ16309

Phospho-FRS2 (Tyr436) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16309-50, BZ16309-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: Q8WU20

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100

Background: Adapter protein that links FGR and NGF receptors to downstream signaling pathways. Involved in the activation of MAP kinases. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 57 kDa; Observed MW: 65 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-FRS2 in HUVEC lysates using Phospho-FRS2 antibody., Immunohistochemistry analysis of paraffin-embedded Human brain tissue using FRS2 antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval. Sample with blocking peptide on the right.

Alternative Name: Fibroblast growth factor receptor substrate 2; FGFR substrate 2; FGFR-signaling adaptor SNT; Suc1-associated neurotrophic factor target 1; SNT-1

Immunogen: Synthetic peptide of human FRS2

Conjugate: Unconjugated

Modification: Phosphorylated