Phospho-GCN2 (Thr667) Polyclonal Antibody-BZ17061

Phospho-GCN2 (Thr667) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17061-50, BZ17061-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q9P2K8

Host: Rabbit

Reactivity: Human

Applications: WB,IP

All Applications: WB: 1/500-1/1000 IP: 1/20

Background: This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-GCN2 in Hela, HepG2, 293TLysates using Phospho-GCN2 antibody.

Bioworld Molecular Weight: Calculated MW: 187 kDa; Observed MW: 220 kDa

Specificity: IgG

Alternative Name: GCN2-like protein; GCN2; KIAA1338; EIF2AK4

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Thr667 of human GCN2

Conjugate: Unconjugated

Modification: Phosphorylated