Product Description

Phospho-Glutamate Receptor 1 (AMPA Subtype) (Ser845) Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB10536-50, MB10536-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P42261

Host: Rabbit

Reactivity: Human, Rat

Applications: WB,

All Applications: WB: 1/500-1/1000

Background: AMPA- (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainate-, and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4), which assemble as homo- or hetero-tetramers to mediate the majority of fast excitatory transmissions in the central nervous system. AMPARs are implicated in synapse formation, stabilization, and plasticity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 102 kDa; Observed MW: 102 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Glutamate Receptor 1 in U87-MG lysates using Phospho-Glutamate Receptor 1 antibody., Western blot analysis of Phospho-Glutamate Receptor 1 in C6 lysates using Phospho-Glutamate Receptor 1 antibody.

Alternative Name: GRIA1; GLUH1; GLUR1; Glutamate receptor 1; GluR-1; AMPA-selective glutamate receptor 1; GluR-A; GluR-K1; Glutamate receptor ionotropic; AMPA 1; GluA1

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser845 of human AMPA Receptor 1 (GluA1)

Conjugate: Unconjugated

Modification: Phosphorylated