Phospho-HDAC6 (Ser22) Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-21286-60, E-AB-21286-120, E-AB-21286-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: HDAC6 (phospho Ser22)
Target Synonym: CPBHM; FLJ16239; HD 6; HD6; HDAC 6; HDAC6; HDAC6; Histone deacetylase 6 (HD6); Histone deacetylase 6; JM 21; JM21; KIAA0901; OTTHUMP00000032398; OTTHUMP00000197663; PPP1R90; Protein phosphatase 1 regulatory subunit 90
Research Areas: Cancer, Epigenetics and Nuclear Signaling, Stem Cells
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: WB, IHC-p, IF, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q9UBN7
Background: Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Concentration: 1 mg/mL
Immunogen: Synthesized peptide derived from human HDAC6 around the phosphorylation site of Ser22
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method: Affinity purification
Dilution: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
Calculated MW: 131kDa
Observed MW: 131kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only