Product Description

Phospho-Histone H3 (S10) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40010-50, BS40010-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellμlar machineries which require DNA as a template.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, IP

Alternate Names: H3 histone, family 3A, H3 histone, family 3B (H3.3B), H3.3A, H3.3B, H33, H3F3, H3F3A, H3F3B, Histone H3.3,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-Histone H3 (S10)

Dilution: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

Purification: Affinity-chromatography

Specificity: Phospho-Histone H3 (S10) Antibody detects endogenous levels of total Phospho-Histone H3 (S10)

Molecular Weight: ~ 18 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P68431

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only