Phospho-IGF1 Receptor (Tyr1165/Tyr1166) Polyclonal Antibody-BZ16111

Phospho-IGF1 Receptor (Tyr1165/Tyr1166) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16111-50, BZ16111-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P08069

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, ELISA

All Applications: WB: 1/500-1/1000 ELISA: 1/10000

Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 155 kDa; Observed MW: 155 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-IGF1 Receptor in various lysates using Phospho-IGF1 Receptor antibody., Western blot analysis of Phospho-IGF1 Receptor in COS7 lysates using Phospho-IGF1 Receptor antibody.

Alternative Name: IGF1R; Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD antigen CD221

Immunogen: The antiserum was produced against synthesized peptide derived from human IGF1R around the phosphorylation site of Tyr1165/Tyr1166. AA range:1131-1180

Conjugate: Unconjugated

Modification: Phosphorylated