Product Description

Phospho-IGF1 Receptor (Tyr1166) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB11111-50, MB11111-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This receptor binds insμlin-like growth factor with a high affinity. It has tyrosine kinase activity. The insμlin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IP

Alternate Names: IGF1R, Insμlin-like growth factor 1 receptor, Insμlin-like growth factor I receptor, IGF-I receptor, CD antigen CD221

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Tyr1166 of human INSR/IGF-1R

Dilution: WB: 1/500-1/1000 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 155 kDa, Observed MW: 95 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P08069

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only