Product Description

Phospho-IRAK1 (Ser376) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS65624-50, BS65624-100

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Swiss-Prot: Q62406

Host: Rabbit

Reactivity: Human, Mouse, Rat, Dog, Rabbit,

Applications: IHC-P

All Applications: IHC-P=1:100-500 IHC-F=1:100-500

Background: This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Purification and Purity: affinity purified by Protein A

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Phospho-IRAK1 (Ser376) Polyclonal Antibody detects endogenous levels of Phospho-IRAK1 protein only when phosphorylated at Ser376

Bioworld Molecular Weight: 78kD

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Tissue/cell: mouse kidney tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,) at 37℃ for 20 min;
Incubation: Anti-Phospho-FRA1 (Ser265) Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C, Tissue/cell: human gastric cancer; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,) at 37℃ for 20 min;
Incubation: Anti-Phospho-IRAK1 (Ser376) Polyclonal Antibody, Unconjugated 1:200, overnight at 4°C

Alternative Name: IRAK (phospho S376); p-IRAK (phospho S376); IRAK1 (Phospho-Ser376); IRAK1 (Phospho-S376); IRAK1 (p-Ser376); Il1rak; Il1rak; Interleukin 1 receptor associated kinase 1; Interleukin 1 receptor associated kinase 1; Interleukin 1 receptor associated kinase 2; Interleukin-1 receptor-associated kinase 1; IRAK; IRAK-1; IRAK1; IRAK1; IRAK1_HUMAN; IRAK2; IRAK2; mPLK; mPLK; Pelle; Pelle; Pelle homolog; Pelle-like protein kinase; Plpk.

Immunogen: KLH conjugated synthetic peptide derived from mouse Phospho-IRAK1 (Thr209):QS(p-S)t V

Conjugate: Unconjugated

Modification: Phosphorylation