Product Description

Phospho-LAT (Y220) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40034-50, BS40034-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobμlin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobμlin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellμlar events such as mobilization of intracellμlar calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecμles.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, IP

Alternate Names: 36 kDa phospho-tyrosine adaptor protein, LAT1, lat, pp36

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-LAT (Y220)

Dilution: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:30

Purification: Affinity-chromatography

Specificity: Phospho-LAT LAT (Y220) Antibody detects endogenous levels of total Phospho-LAT (Y220)

Molecular Weight: 38kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O43561

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only