Product Description

Phospho-Leptin Receptor (Tyr1141) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16334-50, BZ16334-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regμlating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regμlates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity).

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Alternate Names: Leptin receptor, LEP-R, HuB219 OB receptor, OB-R, CD295, LEPR, DB, OBR

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: Synthetic peptide of human LEPR

Dilution: WB: 1/500-1/1000 ELISA: 1/10000

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 132 kDa, Observed MW: 132 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P48357

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only