Phospho-Leptin Receptor (Tyr1141) Polyclonal Antibody-BZ16334

Phospho-Leptin Receptor (Tyr1141) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16334-50, BZ16334-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P48357

Host: Rabbit

Reactivity: Human, Mouse

Applications: WB,ELISA

All Applications: WB: 1/500-1/1000 ELISA: 1/10000

Background: On ligand binding, mediates LEP central and peripheral effects through the activation of different signaling pathways such as JAK2/STAT3 and MAPK cascade/FOS. In the hypothalamus, LEP acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones (By similarity).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Leptin Receptor in K562Lysates using Phospho-Leptin Receptor antibody.

Bioworld Molecular Weight: Calculated MW: 132 kDa; Observed MW: 132 kDa

Specificity: IgG

Alternative Name: Leptin receptor; LEP-R; HuB219 OB receptor; OB-R; CD295; LEPR; DB; OBR

Immunogen: Synthetic peptide of human LEPR

Conjugate: Unconjugated

Modification: Phosphorylated