Phospho-LIM Kinase 1 (Thr508) Polyclonal Antibody-BZ16295

Phospho-LIM Kinase 1 (Thr508) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16295-50, BZ16295-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P53667

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Background: Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 73 kDa; Observed MW: 73 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-LIM Kinase 1 in C2C12, Hela, 293 lysates using Phospho-LIM Kinase 1 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using LIMK1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-LIM Kinase 1 in Hela cells using LIMK1 antibody.

Alternative Name: LIMK1; LIMK; LIM domain kinase 1; LIMK-1

Immunogen: Synthetic peptide of human LIMK1

Conjugate: Unconjugated

Modification: Phosphorylated