Product Description

Phospho-LRRK2 (Ser395) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16573-50, BZ16573-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Positively regμlates autophagy through a calcium-dependent activation of the CaMKK/AMPK signaling pathway. The process involves activation of nicotinic acid adenine dinucleotide phosphate (NAADP) receptors, increase in lysosomal pH, and calcium release from lysosomes. Together with RAB29, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner.

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ICC/IF

Alternate Names: AURA17, Dardarin antibody, , Leucine rich repeat kinase 2, LRRK 2 antibody, LRRK2, LRRK2_HUMAN, PARK 8, PARK8, RIPK7, ROCO 2, ROCO2

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-LRRK2 (S935)

Dilution: WB: 1/500-1/1000 IF: 1/50-1/200

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 286 kDa, Observed MW: 286 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q5S007

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Research Use Only