Product Description

Phospho-MEK4 (Ser80) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB11875-50, MB11875-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for mμltiple biochemical signals and are involved in a wide variety of cellμlar processes such as proliferation, differentiation, transcription regμlation, and development. They form a three-tiered signaling modμle composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing resμlts in mμltiple transcript variants. [provided by RefSeq, Jμl 2013]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IP

Alternate Names: MAP2K4, JNKK1, MEK4, MKK4, PRKMK4, SEK1, SERK1, SKK1, Dual specificity mitogen-activated protein kinase kinase 4, MAP kinase kinase 4, MAPKK 4, JNK-activating kinase 1, MAPK/ERK kinase 4, MEK 4, SAPK/ERK kinase 1, SEK1, Stress-activated pro

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4

Dilution: WB: 1/500-1/1000 IP: 1/20

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 44 kDa, Observed MW: 44 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P45985

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Research Use Only