Product Description

Phospho-mTOR (Thr2446) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16319-50, BZ16319-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P42345

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-mTOR in 3T3Lysates using Phospho-mTOR antibody.

Bioworld Molecular Weight: Calculated MW: 289 kDa; Observed MW: 220 kDa

Specificity: IgG

Alternative Name: MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar

Immunogen: Synthetic peptide of human MTOR

Conjugate: Unconjugated

Modification: Phosphorylated