Product Description

Phospho-Myosin Phosphatase (Thr853) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16388-50, BZ16388-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O14974

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: ICC/IF,WB,IHC-F,IHC-P,ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 ELISA: 1/10000

Background: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Primary Antiboies of Zen Bio were identified for Q&C tests by multiimmunology applications which were performed with different cell or tissue samples.

Bioworld Molecular Weight: Calculated MW: 115 kDa; Observed MW: 130 kDa

Specificity: IgG

Alternative Name: PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit

Immunogen: The antiserum was produced against synthesized peptide derived from human MYPT1 around the phosphorylation site of Thr853. AA range:621-670

Conjugate: Unconjugated

Modification: Phosphorylated