Product Description

Phospho-p53 (S392) Rabbit Monoclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Sizes: 50µl, 100µl

Catalogue Numbers: BS40079-50, BS40079-100

Swiss-Prot: P04637

Host: Rabbit

Phospho-p53 (S392) Rabbit Monoclonal Antibody-BS40079

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Reactivity: Human, Mouse, Rat

Applications: WB, IHC ICC/IF, IP,

All Applications: WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50

Background: Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains.

Purification and Purity: Affinity-chromatography

Specificity: Phospho-p53 (S392) Antibody detects endogenous levels of total Phospho-p53 (S392)

Bioworld Molecular Weight: 53kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-p53 (Ser392) expression in HEK293 whole cell lysate., Immunohistochemical analysis of paraffin-embedded human breast, using Phospho-p53 (S392) Antibody.

Alternative Name: Antigen NY-CO-13, Cellular tumor antigen p53, Phosphoprotein p53, TP53, Tumor suppressor p53

Immunogen: A synthesized peptide derived from human Phospho-p53 (S392)

Modification: Phosphorylated

Conjugate: Unconjugated