Product Description

Phospho-p53 (T55) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40151-50, BS40151-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Plays an essential role in the regμlation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postμlated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor.

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB

Alternate Names: Antigen NY-CO-13, TP53, Tumor suppressor p53, Cellμlar tumor antigen p53, Phosphoprotein p53

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-p53 (T55)

Dilution: WB 1:500~1:2000

Purification: Affinity-chromatography

Specificity: Phospho-p53 (T55) Antibody detects endogenous levels of total Phospho-p53 (T55)

Molecular Weight: 53kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P04637

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only