Phospho-Presenilin 1 (Ser310) Monoclonal Antibody
Sizes: 50µl, 100µl
Catalogue Numbers: MB10407-50, MB10407-100
Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Swiss-Prot: P49768
Host: Rabbit
Reactivity: Human
Applications: WB
All Applications: WB: 1/500-1/1000
Background: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity.
Purification and Purity: Affinity Purified
Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Note: For research use only, not for use in diagnostic procedure.
Extra Notes: Western blot analysis of Phospho-Presenilin 1/PS1 in Jurkat, HelaLysates using Phospho-Presenilin 1 antibody.
Bioworld Molecular Weight: Calculated MW: 53 kDa; Observed MW: 22 kDa
Specificity: IgG
Alternative Name: PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182
Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser310 of human Presenilin 1
Conjugate: Unconjugated
Modification: Phosphorylated