Product Description

Phospho-Raf1 (S43) Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40359-50, BS40359-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. Activated ERKs are pleiotropic effectors of cell physiology and play an important role in the control of gene expression involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB

Alternate Names: C-Raf, CRAF, Protein kinase raf 1, RAF1, Raf proto-oncogene serine/threonine-protein kinase, kinase Raf1,

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-Raf1 (S43)

Dilution: WB 1:500~1:1000

Purification: Affinity-chromatography

Specificity: Phospho-Raf1 (S43) Antibody detects endogenous levels of total Phospho-Raf1 (S43)

Molecular Weight: 73kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P04049

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only