Product Description

Phospho-SIRT1 (Ser47) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17059-50, BZ17059-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q96EB6

Host: Rabbit

Reactivity: Human

Applications: WB,IHC-F,IHC-P,ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-SIRT1 in A549Lysates using Phospho-SIRT1 antibody.

Bioworld Molecular Weight: Calculated MW: 82 kDa; Observed MW: 120 kDa

Specificity: IgG

Alternative Name: SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2

Immunogen: A synthetic phosphopeptide corresponding to residues surrounding Ser47 of human SIRT1

Conjugate: Unconjugated

Modification: Phosphorylated