Product Description

Phospho-Src (Tyr419) Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BZ16612-50, BZ16612-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Src activity is regμlated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregμlates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, FC

Alternate Names: SRC, SRC1, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, pp60c-src, p60-Src

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Phosphorylated

Immunogen: A synthesized peptide derived from human Phospho-Src (Y419)

Dilution: WB: 1/500-1/1000 FC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG

Molecular Weight: Calcμlated MW: 60 kDa, Observed MW: 60 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P12931

Product: Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Research Use Only