Product Description

Phospho-Syk (Tyr348) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16329-50, BZ16329-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P43405

Host: Rabbit

Reactivity: Human, Mouse, Rat, Monkey

Applications: WB, IHC-P, ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 72 kDa; Observed MW: 72 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-Syk in 3T3 lysates using Phospho-Syk antibody., Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-Syk antibody. High-pressure and temperature Sodium Citrate pH 6. 0 was used for antigen retrieval. Sample with blocking peptide on the right.

Alternative Name: SYK; Tyrosine-protein kinase SYK; Spleen tyrosine kinase; p72-Syk

Immunogen: Synthetic peptide of human SYK

Conjugate: Unconjugated

Modification: Phosphorylated