Phospho-TAK1 (Thr187) Polyclonal Antibody-BZ16172

Phospho-TAK1 (Thr187) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16172-50, BZ16172-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: O43318

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB,IHC-P,ELISA

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ELISA: 1/10000

Background: Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-TAK1 in 293TLysates using Phospho-TAK1 antibody.

Bioworld Molecular Weight: Calculated MW: 67 kDa; Observed MW: 60 kDa

Specificity: IgG

Alternative Name: MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Immunogen: The antiserum was produced against synthesized peptide derived from human MAP3K7 around the phosphorylation site of Thr187. AA range:161-210

Conjugate: Unconjugated

Modification: Phosphorylated