Product Description

Phospho-VEGF Receptor 2 (Tyr1214) Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ16293-50, BZ16293-100

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Swiss-Prot: P35968

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 ICC: 1/100-1/200

Background: VEGFR-2 is a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 152 kDa; Observed MW: 230 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Phospho-VEGF Receptor 2 in mouse kidney, rat kidney lysates using Phospho-VEGF Receptor 2 antibody., Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using VEGFR2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right., Immunofluorescence analysis of Phospho-VEGF Receptor 2 in MCF-7 cells using VEGFR2 antibody.

Alternative Name: KDR; FLK1; VEGFR2; Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD antigen CD309

Immunogen: Synthetic peptide of human KDR

Conjugate: Unconjugated

Modification: Phosphorylated