Phostensin Monoclonal Antibody-MB0157

Phostensin Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB0157-50, MB0157-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q6NYC8

Host: Mouse IgG1

Reactivity: Human

Applications: WB

All Applications: WB: 1:200~1000

Background: In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions, including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases, specifically PP1 (protein phosphhatase 1), which is targeted to different substrates throughout the cell. Phostensin, also known as KIAA1949, is a 613 amino acid protein that localizes to both the cytoplasm and the cytoskeleton. Expressed predominately in spleen, ovary, lung and liver tissue, phostensin functions as a regulatory subunit that interacts with and targets PP1 to F-Actin in the cytoskeleton. Two isoforms of phostensin exist due to alternative splicing events.

Purification and Purity: The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This antibody detects endogenous levels of Phostensin and does not cross-react with related proteins

Bioworld Molecular Weight: Predicted band size:120KDa
Observed band size:120KDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western BlotDetection of PPP1R18 in Hela, Raji, Ramos&Leucocyte cell lysates and using PPP1R18 antibody (1:200 diluted).

Alternative Name: HKMT1098; KIAA1949; Protein phosphatase 1 F actin cytoskeleton targeting subunit.; PPP1R18;

Immunogen: Recombinant full length Human Phostensin.

Conjugate: Unconjugated

Modification: Unmodified