Product Description

PI 3 kinase p110 alpha Rabbit Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS40084-50, BS40084-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Phosphoinositide-3-kinase (PI3K) that phosphorylates PtdIns (Phosphatidylinositol), PtdIns4P (Phosphatidylinositol 4-phosphate) and PtdIns(4, 5)P2 (Phosphatidylinositol 4, 5-bisphosphate) to generate phosphatidylinositol 3, 4, 5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellμlar signaling in response to various growth factors.

Category: Primary Antibody

Reactivity: Human Mouse Rat

Host: Rabbit

Applications: WB, ICC/IF, IP

Alternate Names: PI 3 Kinase catalytic subunit alpha, phosphoinositide-3-kinase catalytic alpha polypeptide, PI3-kinase p110 alpha, PI3K, PI3K p110-alpha, PK3CA, PIK3CA, PtdIns-3-kinase p110

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: A synthesized peptide derived from human PI 3 Kinase catalytic subunit alpha

Dilution: WB 1:1000~1:2000 ICC/IF 1:50~1:200 IP 1:20

Purification: Affinity-chromatography

Specificity: PI 3 Kinase catalytic subunit alpha detects endogenous levels of total PI 3 Kinase catalytic subunit alpha

Molecular Weight: 110kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P42336

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Research Use Only