PI 3-kinase p85α rabbit pAb - ES3199

PI 3-kinase p85α rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES3199-50, ES3199-100

Citations, Manuals and MSDS Available upon request.

Background: Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011],

Alternate Name: PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alph

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human PI3-kinase p85-alpha. AA range:573-622

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 85kD

Human Gene ID: 5295

Human SWISS Prot NO: P27986

Subcellular Location: nucleus, cytoplasm, cis-Golgi network, cytosol, plasma membrane, cell-cell junction, phosphatidylinositol 3-kinase complex, phosphatidylinositol 3-kinase complex, class IA, membrane, perinuclear endoplasmic reticulum membrane,

Research Use Only