PI 3 kinase p85 alpha Monoclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-22165-60, E-AB-22165-120, E-AB-22165-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PI3 Kinase P85α
Target Synonym: GRB1; p85 alpha; p85; P85A; Phosphatidylinositol 3 kinase associated p 85 alpha; Phosphatidylinositol 3 kinase regulatory 1; Phosphatidylinositol 3 kinase; regulatory subunit; polypeptide 1 (p85 alpha); Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphoinositide 3 kinase; regulatory subunit 1 (alpha); PI3 kinase p85 subunit alpha; PI3-kinase regulatory subunit alpha; PI3-kinase subunit p85-alpha; PI3K; PI3K regulatory subunit alpha; Pik3r1; PtdIns 3 kinase p85 alpha; PtdIns-3-kinase regulatory subunit alpha; PtdIns-3-kinase regulatory subunit p85-alpha
Research Areas: Cancer, Metabolism, Immunology, Signal Transduction
Conjugation: Unconjugated
Host: Mouse
Species Reactivity: Mouse, Rat
Application: WB, IHC-p
Isotype: IgG
Clonality: Monoclonal
Clone No.: 2D2
UNIProt ID: P27986
Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues.
Concentration: 1 mg/mL
Immunogen: Recombinant Protein
Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4
Purification Method: Protein A purification
Dilution: WB 1:1000-2000, IHC 1:100-200
Observed MW: 85kDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only