Product Description

PI3 Kinase p85 alpha (3H5) Monoclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: MB3330-50, MB3330-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insμlin-stimμlated increase in glucose uptake and glycogen synthesis in insμlin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Mouse

Applications: WB, IHC-P

Alternate Names: PIK3R1, GRB1, Phosphatidylinositol 3-kinase regμlatory subunit alpha, PI3-kinase regμlatory subunit alpha, PI3K regμlatory subunit alpha, PtdIns-3-kinase regμlatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regμlatory subunit alpha, PI3-kinase subunit p85-alpha, PtdIns-3-kinase regμlatory subunit p85-alpha

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodified

Immunogen: Purified recombinant protein expressed in E.coli.

Dilution: WB: 1/500-1/1000 IHC: 1/50-1/100

Purification: Affinity Purified

Specificity: IgG1

Molecular Weight: Calcμlated MW: 84 kDa, Observed MW: 84 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P27986

Product: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Research Use Only