Product Description

PI3 Kinase p85 alpha Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB12191-50, MB12191-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P27986

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1/500-1/1000

Background: Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PI 3 Kinase p85 alpha in HL-60, U2OS, C6Lysates using PI3 Kinase p85 alpha antibody.

Bioworld Molecular Weight: Calculated MW: 84 kDa; Observed MW: 84 kDa

Specificity: IgG

Alternative Name: PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase subunit p85-alpha; PtdIns-3-kinase regulatory subunit p85-alpha

Immunogen: A synthetic peptide of human PI 3 Kinase p85 alpha

Conjugate: Unconjugated

Modification: Unmodified