Product Description

PIAS 3 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28751-50, RA28751-100

Citations, Manuals and MSDS Available upon request.

Background: protein inhibitor of activated STAT 3 (PIAS3) Homo sapiens This gene encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription) ] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier) -E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of this gene have been identified, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: PIAS3; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 10401

Protein MW (KDa): 68

SWISS: Q9Y6X2

Source: Rabbit

Research Use Only