Product Description

PIASx Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28752-50, RA28752-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: protein inhibitor of activated STAT 2 (PIAS2) Homo sapiens This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011],

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Applications: WB, ELISA

Alternate Names: PIAS2, PIASX, E3 SUMO-protein ligase PIAS2, Androgen receptor-interacting protein 3, ARIP3, DAB2-interacting protein, DIP, Msx-interacting zinc finger protein, Miz1, PIAS-NY protein, Protein inhibitor of activated STAT x, Protein inhibitor

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Molecular Weight: 68

Protein Molecular Weight (kDa): 68

Storage: -20°C/1 year

Human Gene ID: 9063

Human SwissProt Number: O75928

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only